Polymerase Chain Reaction and In Situ Hybridization: Applications in Toxicological Pathology
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منابع مشابه
Fluorescent in Situ Hybridization and Real-Time Quantitative Polymerase Chain Reaction to Evaluate HER-2/neu Status in Breast Cancer
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Immunohistochemistry (IHC) has been successfully used to detect protein products and infective, microbial or viral particles in cells. One of its limitations is its inability to detect these agents when they are present in minute quantities. In situ hybridization (ISH) has an advantage over immunohistochemistry in its ability to demonstrate specific messenger RNA (mRNA). ISH can be combined wit...
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The movie J7urassic Park and real life events like the 0 J Simpson trial have captured public interest in molecular biology. The basis of molecular biology is the understanding of the structure and function of DNA, RNA, and proteins, as well as the techniques for manipulating these molecules. In this review we demonstrate how a single technique revolutionised this research area and made molecul...
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ژورنال
عنوان ژورنال: Toxicologic Pathology
سال: 1996
ISSN: 0192-6233,1533-1601
DOI: 10.1177/019262339602400104